A septal myectomy is an open heart surgical procedure that reduces thickened heart muscle in patients with hypertrophic cardiomyopathy. In this procedure, your surgeon will make a cut in the center of your chest to access your heart and remove a portion of the overgrown septum (muscular wall separating the left and right sides of the lower heart chambers). Recovery usually involves one or two days of recovery in intensive care after the surgery, followed by five to seven more days of recovery time in the hospital.